Desplan Lab
New York University. 100 Washington Square East.
1009 Silver Center. New York, NY. 10003.

Post-Doctoral Fellow

Miriam Rosenberg



mr166@nyu.edu

(212) 992-9526

CV


Education

  • 2005. University of Washington, Seattle. PhD.

Interests

  • Signaling from maternal and gap genes are integrated at the level of the pair rule genes in Drosophila whose promoters carry both stripe specific enhancer elements that translate local TF concentration of upstream genes into segment identity and position along the A-P axis. We are working to understand how known gap and maternal genes regulate the Nasonia pair rule genes. Nasonia even-skipped exhibits characteristics of both long- and short-germ insects in its segmental expression and function. We are currently establishing how this pattern is achieved by upstream genes and aim to identify enhancers that control eve expression. We are also studying how other pair rule genes are expressed and regulated in Nasonia. Our loss of function data for this class of genes support a model in which there are two modes of segment patterning in Nasonia: an anterior, simultaneous mode that resembles that of Drosophila, and a posterior sequential mode that resembles that of ancestral (short germ) insects. It will be of paramount interest to investigate how these two modes can co-exist and resolve during the evolution of long germ embryogenesis.

Funding

  • Fulbright Postdoctoral Fellowship - Current
  • American Cancer Society Postdoctoral Research Fellowship - Current
  • NIH Ruth Kirschstein NRSA Postdoctoral Research Fellowship