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Faculty Information

Michael C. Alfano, D.M.D., Ph.D.
Professor
Basic Science and Craniofacial Biology
Room 1219 Bobst Library, 70 Washington Square South
Fax: 212-995-4789
E-mail:

 

Education:

1967 Biology, Rutgers University
1971 D.M.D., University of Medicine & Dentistry of New Jersey
1971-1973 Harvard University School of Dental Medicine, Trainee in Periodontics
1971-1974 Ph.D., Nutritional Biochemistry & Oral Biology, Massachusetts Inst. of Technology, Dept. of Nutrition & Food Science,
1976 Certificate in Periodontics, Fairleigh Dickinson University, School of Dentistry

 

Research Interests / Professional Overview:

Improving the Quality and Efficiency of Higher Education, especially Dental Education

Enhancing Oral and General Health through Better Therapy, Public Education, and
Challenging the Dental Profession

Promotion of Improved Interactions Among Academic, Industrial and Government
Scientists, the Regulatory Agencies and the Public

Evaluation of New Products for the Personal Care, Dental, and Pharmaceutical Industries

Pathogenesis and Therapy of Periodontal Disease; Nutrition in Oral Health

 

Pub Med Articles:

Alfano MC

 

Representative Publications:

Alfano, M.C.: "The Origin of Gingival Fluid" J. Theoretical Biol.47: 127-136, 1974

Alfano, M.C., Morhart, R., Metcalf, G. and Drummond, J.F.: "Presence of Collagenase from
Clostridium Histolyticum in Gingival Sulcal Debris of a Primitive Population" J.
Dent. Res. 53:142, 1974

Alfano, M.C.: "The Effect of Ascorbic Acid Deficiency on the Barrier Function of Guinea-
Pig Oral Mucosal Epithelium" Doctoral Thesis, 1974, Institute Archives, Massachusetts Institute of Technology
Alfano, M.C., Drummond, J.F., and Miller, S.A.: "Technique for Studying the Dynamics of
Oral Mucosal Permeability in Vitro" J. Dent. Res. 54: 194, 1975

Alfano, M.C., Miller, S.A., Drummond, J.F.: "Effect of Ascorbic Acid Deficiency on the Permeability and Collagen Biosynthesis of Oral Mucosal Epithelium" Ann. NY Acad. Sci. 258:253-263, 1975

Alfano, M.C., Drummond, J.F., and Miller, S.A.: "Localization of the Rate-Limiting Barrier to the Penetration of Endotoxin through Non-Keratinized Oral Mucosa In Vitro" J. Dent. Res. 54: 1180-1182, 1975

Inouye, L., Miller, S.A. and Alfano, M.C.: "The Lingual Ascorbic Acid Test: Lack of
Correlation with Blood and Tissue Levels of Ascorbic Acid in Guinea-Pigs" J. Dent
Res. 54:1143-1148, 1975

Alfano, M.C.: "The Role of the Host in Periodontal Disease" J.W. S. .Perio. 23:105-107, 1975

Alfano, M.C.: "Controversies, Perspectives and Clinical Implications of Nutrition in Periodontal Disease" Dent. Clin. North Amer. 20:519-548, 1976

DePaola, D.P. and Alfano, M.C.: "Tri-Phasic Nutritional Analysis" Dent. Clin. North Amer. 20: 613-633, 1976

Alfano, M.C., Kaslick, R.S., Chasens, A.I. and Brownstein, C.N.: "Passively Generated Increase in Human Gingival Crevicular Fluid Flow" J. Dent. Res. 55:1132, 1976

DePaola, D.P. and Alfano, M.C.: "Nutrition and Oral Health" Nutrition Today 12:6-32, 1977

Feingold, J., Chasens, A.I., Doyle, J.L. and Alfano, M.C.: "Preserved Scleral Allografts in Periodontal Defects in Man" J. Periodont. 48:4-12, 1977

Alfano, M.C., Chasens, A.I. and Masi, C.W.: "Autoradiographic Study of the Penetration of Radiolabelled Dextrans and Inulin through Non-Keratinized Oral Mucosa In Vitro" J. Periodont. Res. 12:368-377, 1977

Alfano, M.C.: "Prospective Improvements in the Prevention of Periodontal Disease" J. Prev. Dent. 5:26-29, 1978

Alfano, M.C., DePaola, D.P.: "Methods for Assessing Nutritional Status in Dental Practice" Quintessence Int. 9:115-125, 1978

Alfano, M.C.: "Effect of Acute Ascorbic Acid Deficiency on the DNA Content and Permeability of Guinea-Pig Oral Epithelium" Archs. Oral Biol. 23:929-932, 1978

Gillespie, B.R., Chasens, A.I., Brownstein, C.N. and Alfano, M.C.: "Relationship Between the Mobility of Human Teeth and Their Supracrestal Fiber Support" J. Perio. 50:120-124, 1979

Saroff, S., Alfano, M.C., Chasens, A.I. and King, W.: "Sonicated Passively Dispersed Hydrogen Peroxide in Periodontitis: Effects on Clinical Parameters and Myeloperoxidase Activity" J. Perio. Res. 15:216-222, 1980

Alfano, M.C.: "Nutrition, Sweeteners and Dental Caries" J. Food Tech. 34:70-74, 1980

Vogel, R.I., Deasy, M.J., Alfano, M.C. and Schneider, L.C.: "Effect of Folic Acid on Gingival
Health in Women Taking Contraceptives" J. Prev. Dent. 6:221-227, 1980

Alfano, M.C.: "Diet and Nutrition in the Etiology and Prevention of Oral Disease" J. Dent. Res. 59:2194-2202, 1980

Alfano, M.C.: "Dental Caries: The Nature of the Problem" Cereal Foods 26:5-9, 1981

Vogel, R.I., Alfano, M.C. and Manhold, J.H.: "The Effect of Intrasulcular Brushing on Sulcular Epithelial Permeability" J. Periodont. 52:224-250, 1981

Alfano, M.C.: "Nutrition in Dental Practice: A Plea for Sanity" New York State Dent. J. 47:450-452, 1981

Ritchey, T.W., Lamster, I.B., Mann, P.H. and Alfano, M.C.: "The Effect of Zinc Chloride on the Development of Gingivitis in Beagle Dogs Treated with Cetylpyridinium Chloride" J.Dent. Res. 61:1217-1220, 1982

Lamster, I.B., Alfano, M.C., Seiger, M.C., Gordon, J.M.: "The Effect of Listerine Antiseptic on Reduction of Existing Plaque and Gingivitis" Clin. Prev. Dent. 5:12-16, 1983

Howell, T.H., Reddy, M.S., Li, K.L., Alfano, M.C., Weber, H.P., Kaplan, M.C., Vogel, R., Williams, R.C.: "Inhibition of Plaque Formation, Prevention and Treatment of Gingivitis with Sulfadiazines in Beagles" J. Dent. Res. 68 (Spec. Issue): 1712-1713, 1989

Howell, T.H., Reddy, M.S., Weber, H.P., Li, K.L., Alfano, M.C., Vogel, R., Tanner, A.C.R., Williams, R.C.: "Sulfadiazines Prevent Plaque Formation and Gingivitis in Beagles" J. Periodont. Res. 25:197-200, 1990

Howell, T.H., Reddy, M.S., Weber, H.P., Li, K.L., Alfano, M.C., Vogel, R., Tanner, A.C.R., and Williams, R.C.: "Sulfadiazines Reduce Gingivitis and Plaque Formation in Beagle Dogs" J. Clin. Periodontol. 17:734-737, 1990

Smith, M.A., Braswell, L.D., Collins, J.G., Boyd, D.L., Jeffcoat, M.K., Reddy, M., Li, K.L., Wilensky, S., Vogel, R., Alfano, M.C. and Offenbacher, S.: "Changes in Inflammatory Mediators in Experimental Periodontitis in the Rhesus Monkey" Infection and Immunity 61:1453-1459, 1993

Li, K.L., Vogel, R., Jeffcoat, M.K., Alfano, M.C., Smith, M.A., Collins, J.G.,
Offenbacher, S: "The Effects of Ketoprofen Creams on Periodontal Disease in Rhesus
Monkeys" J. Periodont. Res. 31:525-531, 1996

Khandwala, A., Van Inwegen, R.G., Alfano, M.C.: "5% Amlexanox Oral Paste A New Treatment for Recurrent Minor Aphthous Ulcers I. Clinical Demonstration of Acceleration of Healing and Resolution of Pain" Oral Surg Oral Med Oral Path Oral Radiol Endod 83:222-230, 1997

Khandwala, A., Van Inwegen, R.G., Charney, M.R. Alfano, M.C.: "5% Amlexanox Oral Paste A New Treatment for Recurrent Minor Aphthous Ulcers II. Pharmacokinetics and Demonstration of Clinical Safety" Oral Surg Oral Med Oral Path Oral Radiol Endod 83:231-238, 1997

Alfano, M.C.: "Dental Education: One Dean's Perspective" Journal Am College Dent. 68:8-12, 2002

Alfano, M.C.: "Titanium and Terrorism: The role of the implant dentist. Journal of ICOI (in press) 2003

Gordon, S.M., Heft, M.W., Dionne, R.A., Jeffcoat, M.K., Alfano, M.C., Valachovic, R.V., Lipton, J.A.: Capacity for Training in Clinical Research: Status and Opportunities J. Dent. Educ. 67:622-629, 2003

More, F.G., Phelan, J., Boylan, R., Glotzer, D., Psoter, W., Robbins, M., Rekow, E.D, Alfano, M.C.: "Predoctoral Dental School Curriculum for Catastrophe Preparedness" J. Dent. Ed. 68: 851-858, 2004.

Psoter, W.J., Alfano, M.C., Rekow, E.D.: "Meeting a Disaster's Medical Surge Demand"
CDA Journal 32: 694-700, 2004

Spielman, A.I., Fulmer, T., Eisenberg, E.S., Alfano, M.C.: "Dentistry, Nursing and Medicine: A Comparison of Core Competencies" J. Dent. Ed. 69: 1257-1271, 2005

Glotzer, D., More, F.G., Phelan, J., Boylan, R., Psoter, W.J., Robbins, M., Rekow, E.D., Godder, B., Alfano, M.C.: "Introducing a Senior Course on Catastrophe Preparedness into the Dental School Curriculum" J. Dent. Ed. (Submitted)

Petropoulis, V.C., Arbree, N.S., Tarnow, D., Rethman, M., Malmquist, J., Valachovic, R., Brunson, W.D., Alfano, M.C.: "Dean's American Dental Education Association Implant Workshop Survey" J. Dent. Ed. (Submitted)