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Faculty Information

John L Ricci, Ph.D.
Associate Professor
Biomaterials and Biomimetics
Room 815S Dental Center, 421 First Avenue
E-mail:

 

Education:

1977 B.S., Muhlenberg College
1984 Ph.D., University of Medicine and Dentistry of New Jersey

 

Research Interests / Professional Overview:

Current projects include development of controlled microtexture surfaces for dental implants that promote bone, connective tissue, and epithelial attachment. The laser micromachined surface of the LaserLokT implant, produced by BioLok International is one of these projects, and additional surfaces are under development. These surfaces are also being applied to other transcutaneous implants that will be used for support of bone conduction hearing aids and prosthetics used for amputees. A timed-release calcium sulfate (CS-TR) composite bone graft substitute, comprising combinations of calcium sulfate and poly-L-lactic acid, is another project currently under development and testing. This material will be used in place of autogenous bone grafts for repair of craniofacial bone defects. Dr. Ricci is also working on development of three-dimensionally printed scaffolds, consisting of permanent and resorbable biomaterials, for replacement and regeneration of craniofacial bone and soft tissue structures. He is also actively researching new methodologies for analysis and imaging of bone and soft tissue structure, and the interface between tissues and biomaterials.

 

Current Funding:

Use of Enamel Matrix Proteins to Induce a Cementum Seal After Endodontic Therapy - NYUCD Deans Faculty Research Award.

Multiphasic Calcium Sulfate Bone Repair Material - NIH

 

Pub Med Articles:

Ricci JL

 

Representative Publications:

Books, Book Chapters, and Proceedings

Ricci JL, Alexander H, Nadkarni P, Hawkins M, Turner J, Rosenblum S, Brezenoff L, DeLeonardis D, Pecora G: Biological Mechanisms of Calcium Sulfate Replacement by Bone. In: Bone Engineering, edited by JE Davies, Em2 Inc., Toronto, Ont. Canada, Chapter 30, 332-344, 2000.

Ricci JL, Charvet J, Frenkel SR, Chang R, Nadkarni P, Turner J, Alexander H: Bone Response to Laser Microtextured Surfaces. In: Bone Engineering, edited by JE Davies, Em2 Inc., Toronto, Ont. Canada, Chapter 25, 282-294, 2000.

Ricci JL, Kummer FJ, Scott D, Pedowitz D, Casar RS, Alexander H: Effects of Texturing Techniques on Surface Composition of Metal Orthopaedic Implants. In: Surface Modification Techniques VII, ed TS Sudarshan. Institute of Materials, London, 1994.

Ricci JL, Charvet J, Chang R, Alexander H: Influence of Surface Microgeometry on In Vitro Cell Growth and Migration. In: Surface Modification Techniques VII, ed TS Sudarshan. Insitute of Materials, London, 1994.

Ricci JL, Spivak JM, Blumenthal NC, Alexander H: Modulation of Bone Ingrowth by Surface Chemistry and Roughness. In: The Bone-Biomaterial Interface, edited by JE Davies, University of Toronto Press, Toronto, Ont. Canada. pp. 334-349, 1991.

Parsons JR, Ricci JL, Alexander H, Bajpai PK: Osteoconductive Composite Grouts for Orthopaedic Use. In: Bioceramics: Material Characteristics Versus In Vivo Behavior, edited by P Ducheyne and J Lemons, New York Academy of Science, New York, pp. 190-207, 1988.

Alexander H, Parsons JR, Ricci JL, Bajpai PK, Weiss AB: Calcium Phosphate Ceramic-Based Composites as Bone Graft Substitutes. In: CRC Critical Reviews on Biocompatibility, edited by D Williams, CRC Press, Boca Raton, FL, 4(1):43-77, 1987.

Parsons JR, Tauro JC, Ricci JL, Alexander H, Weiss AB: Comparison of Antigen Extracted, Lyophylized and Glutaraldehyde-Fixed Bovine Xenograft. In: Advances in Biomaterials 6, Biological and Biological and Biomechanical Performance of Biomaterials, edited by P Christel, A Meunier, and AJC Lee, Elsevier (Amsterdam), pp. 141-145, 1986.

Papers

Vasudev DV, Ricci JL, Sabatino C, Li P, Parsons JR: In vivo evaluation of a biomimetic apatite coating grown on titanium surfaces. J Biomed Mater Res 69A: 629-636, 2004

Orsini G, Ricci J, Scarano A, Pecora G, Petrone G, Iezzi G, Piattelli A: Bone-Defect Healing with Calcium-Sulfate Particles and Cement: An Experimental Study in Rabbit. J Biomed Mater Res Part B: Appl Biomater 68B: 199-208, 2004.

Simon JL, Dutta Roy T, Parsons JR, Rekow ED, Thompson VP, Kemnitzer J, Ricci, JL: Engineered cellular response to scaffold architecture in a rabbit trephine defect. J. Biomed Mater Res, 66A:275-282, 2003.

Dutta Roy T, Simon JL, Ricci JL, Rekow ED, Thompson VP, Parsons JR: Performance of degradable composite bone repair products made via three-dimensional fabrication techniques. J. Biomed Mater Res, 66A:283-291, 2003.

Gosain AK, Song L, Riordan P, Amarante MT, Nagy PG, Wilson CR, Toth JM, Ricci JL: A 1-year study of osteoinduction in hydroxyapatite-derived biomaterials in an adult sheep model: Part 1. Plast. Reconstr. Surg. 109:619-630, 2002.

Frenkel SR, Simon J, Alexander H, Dennis M, Ricci JL: Osseointegration on metallic implant surfaces: Effects of microgeometry and growth factor treatment. J. Biomed Mater Res (Applied Biomaterials), 63(6):706-713, 2002.

Soboyejo WO, Nemetski B, Allameh S, Marcantonio N, Mercer C, and Ricci J: Interactions between MC3T3-E1 cells and textured Ti6Al4V surfaces. J Biomed Mater Res. 62:1, 57-72, 2002.

Wells MR, Vaidya U, Ricci JL, and Cristie C: A neuromuscular platform to extract motor signal information from lesioned nerves. J Rehab Res Dev 38:385-390, 2001.

Levine JP, Bradley J, Turk AE, Ricci JL, Benedict JJ, Steiner G, Longaker MT, McCarthy JG: Bone morphogenetic protein promotes vascularization and osteoinduction in preformed hydroxyapatite in the rabbit. Ann Plast Surg 39(2):158-168, 1997.

Frenkel SR, Clancy RM, Ricci JL, Di Cesare PE, Rediske JJ, Abramson SB: Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly. Arth. Rheum. 39(11):1905-1912, 1996.

Breitbart AS, Staffenberg DA, Thorne CHM, Glat PM, Cunningham NS, Reddi AH, Ricci JL, Steiner G: Tricalcium phosphate and osteogenin: a bioactive onlay bone graft substitute. Plast. Reconst Surg 96(3):699-708, 1995.

Leung Y, Walters M, Blumenthal NC, Ricci J, Spivak J: Determination of the mineral phases and structure of the bone-implant interface using Raman spectroscopy. J Biomed Mater Res 29:591-594, 1995.

Damien CJ, Ricci JL, Christel P, Alexander H, Patat J-L: Formation of a calcium phosphate-rich layer on absorbable calcium carbonate bone graft substitute. Calcified Tissue Internat 55:151-158, 1994.

Rosenblum SF, Frenkel S, Ricci JR, Alexander H: Diffusion of Fibroblast Growth Factor from a Plaster of Paris Carrier. J. Applied Biomater. 4:67-72, 1993.

Ricci JL, Blumenthal NC, Spivak JM, Alexander H: Evaluation of a Low-Temperature Calcium Phosphate Particulate Implant Material: Physical-Chemical Properties and In Vivo Bone Response. J Oral Maxillofac Surg 50:969-978, 1992.

Ricci JL, Kummer FJ, Alexander H, Casar RS: Embedded Particulate Contaminants in Textured Metal Implant Surfaces (Technical Note). J Applied Biomater 3(3):225-230, 1992.

Tauro JC, Parsons JR, Ricci J, Alexander H: Comparison of Bovine Collagen Xenografts to Autogenous Graft in the Rabbit Model. Clin Orthop Rel Res 226:371-384, 1991.

Walters, M., Blumenthal, N.C., Leung, Y., Wang, Y., Ricci, J.L., and Spivak, J.M. Molecular structure at the bone-implant interface: a vibrational spectroscopic characterization. Calcified Tissue International 48:368-369, 1991.

Ricci JL, Gona AG, Alexander H: In Vitro Tendon Cell Growth Rates on a Synthetic Fiber Scaffold Material and on Standard Culture Plates. J Biomed Mater Res 25(5):651-666,1991.

Spivak JM, Ricci JL, Blumenthal NC, Alexander H: A New Canine Model to Evaluate the Biological Response of Intramedullary Bone to Implant Materials and Surfaces. J Biomed Mater Res 24(9):1121-1149, 1990.

Ricci JL, Spivak JM, Alexander H, Blumenthal NC, Parsons J R: Hydroxyapatite Ceramics and the Nature of the Bone-Ceramic Interface. Bull Hosp Joint Dis Orthop Inst 49(2):178-191, 1989.