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Faculty Information

Yihong Li, DDS, MPH, DrPH
Basic Science and Craniofacial Biology
Room 1003 Schwartz Hall, 345 East 24Th Street
Fax: 212-995-4087



1983        DDS, Peking University School of Stomatology, China
1983-84  Residency, Peking University School of Stomatology, China
1988        MPH, University of Alabama at Birmingham
1993        DrPH, University of Alabama at Birmingham
1993-94  Post-Doc, University of Alabama at Birmingham 


Research Interests / Professional Overview:

  • Early childhood caries
  • Molecular epidemiology of the oral microbiota
  • Diversity of oral microbiota associated with HIV infection
  • Transmisstion of maternal indigenous bacteria to the infant


Current Funding:

  • Diversity of Lactobacillus associated with severe dental caries. (NIDCR/NIH)
  • Microbial diversity and genetic characterization of cariogenic biofilm. (NIDCR/NIH)
  • Effect of HIV and HAART on oral microbial colonization and diversity. (NIDCR/NIH)



Pub Med Articles:

Li Y


Representative Publications:

Pattanaporn K, Saraithong P, Aleksejuniene J, Khongkhunthian S, Chhun N, Laohapensang P, Li Y. Birth delivery mode, S. mutans colonization and early childhood caries in 3- to 5-year-old Thai children. Community Dentistry and Oral Epidemiology. 2013. First published online: 29 OCT 2012.

Salazar CR, Sun J, Li Y, Francois F, Corby P, Bedi S, Perez-Perez G, Blaser MJ, Dasanayake D, Pei Z, Chen Y*.  Association between selected oral pathogens and gastric precancerous lesions.  PLoS One 2013;8(1):e51604. 

Liu G, Saxena D, Chen Z, Norman RG, Phelan J, Laverty M, Fisch G, Corby P, Abrams A, Malamud D, Li Y. HIV infection affect S. mutans colonization, but not genotypes. J Dent Res. 2012;91:834-40.

Pushalkar S, Ji X, Li Y, Estilo C, Yegnanarayana R, Singh B, Li X, Saxena D. Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma. BMC Microbiol. 2012;12:144.

Caufield PW, Li Y, Bromage TG. Hypoplasia-Associated Severe Early Childhood Caries - A Proposed Definition. J Dent Res. 2012;91:544-50. 

Ji X, Pushalkar S, Li Y, Glickman R, Fleisher K, Saxena D.  Antibiotic effects on bacterial profile in osteonecrosis of the jaw. Oral Dis. 2012;18:85-95.

Saxena D, Li Y, Yang L, Pei Z, Abrams WR, Malamud D. Human microbiome and HIV/AIDS. Curr HIV/AIDS Report. 2012;9:44-51.

Salazar CR, Francois F, Li Y, Corby P, Hays R, Leung C, Bedi S, Segers S, Queiroz E, Sun J,  Wang B, Ho H, Craig R, Cruz G, Blaser MJ, Perez-Perez G, Hayes RB, Dasanayake A, Pei Z, and Chen Y*. Association between oral health and gastric precancerous lesions. Carcinogenesis. 2012;33:399-403.

Chen Z, Trivedi HM, Chhun N, Varnes MV, Saxena D, Xu T, Li Y. Using DGGE and 16S rRNA gene sequence analysis to evaluate changes in oral bacterial composition.  Chinese Journal of Dental Research. 2011;14:95-103.

Pushalkar S, Mane SP, Ji X. Li, Y, Evans C, Crasta O, Morse D, Meagher R, Singh A and  Saxena D. Microbial diversity in saliva of oral squamous cell carcinoma.  FEMS Immunol Med Microbiol. 2011;61:269-277.

Li Y. Controlling sugar consumption still has a role to play in the prevention of dental caries. J Evid Base Dent Pract. 2011;11:24-6.

Liu G, Saxena D, Chen Z, Deng H, Norman RG, W. Abrams, Malamud D, Li Y. Effect of protease inhibitors on quantitative and qualitative assessment of oral microbes.  FEMS Microbiology Letters. 2010;312:63-70.  

Psoter WJ, Ge Y, Russell SL, Chen Z, Katz RV, Jean-Charles G, Li Y. PCR detection of Streptococcus mutans and Aggregatibacter actinomycetemcomitans in dental plaque samples of Haitian adolescents. Clin Oral Investigations. 2010;15:461-9. 

Ge Y, Caufield PW, Fisch G.S. Li Y. S. mutans and S. sanguinis colonization correlated with caries experience in children. Caries Res. 2008;42:444-8.

Douglas J, Li Y, Tinanoff N. A literary review of the association between mutans streptococci between caregivers and their children. Pediatric Dent. 2008;30:375-87.

Li Y, Ismail AI, Ge Y, Tellez M, Chen Z, and Sohn W. Similarity of bacterial profiles in saliva between African-American mother-child dyads. J Clin Microbiol. 2007;45:3082-3085.

Chen Z, Saxena D, Caufield PW, Ge Y, M. Wang, Li Y. Species-specific primers for detection and quantification of Streptococcus mutans in saliva sample. FEMS Microbiology Letter. 2007;272:154-162.

Li Y, Yao G, Saxena D, Caufield PW. Genetic profiling of the oral microbiota associated with severe early childhood caries. J Clin Microbiol. 2007;45:81-87.

Li Y, Saxena D, Barnes VM, Trivedi HM, Ge Y, Xu T. PCR-based denaturing gradient gel electrophoresis in the evaluation of oral microbiota. Oral Microbiol and Immunol. 2006. 21:333-339.

Li Y, Caufield PW, Dasanayake AP, Wiener H, S. Vermund. Mode of delivery and other maternal factors influence the acquisition of Streptococcus mutants in infants. J Den Res. 2005;84:806-811.

Li Y, Ku CYS, Xu J, Saxena D, Caufield PW. Survey of oral bacterial diversity using PCR-based denaturing gradient gel electrophoresis. J Den Res. 2005;84:559-564.

Li Y, Pan Y, Qi F, Caufield PW. Identification of Streptococcus sanguinis using a PCR-based species-specific DNA probe. J Clin Micribiol. 2003;8:3481-3486.

Li Y, Dasanayake AP, Caufield PW, Elliott RR, Butts, JT. Characterization of maternal mutans streptococci transmission in an African-American Population. Dent Clinics North Am. 2003;47:87-101.

Li Y, Wang W. Predicting caries in permanent teeth from caries in primary teeth. An eight-year cohort study. J Dent Res. 2002;81:561-566.

Li Y, Caufield PW, Emanuelsson I, Thornqvist L. Differentiation of Streptococcus mutans and Streptococcus sobrinus via genotypic and phenotypic profiles from three populations. Oral Microbiol Immunol. 2001;16:16-23.

Li Y, Wang WJ, Caufield PW. The fidelity of mutans streptococci transmission and caries status correlates to breast-feeding experience in Chinese families. Caries Res. 2000;34:123-32.

Li Y, Caufield PW. Arbitrarily primed polymerase chain reaction fingerprinting for the genotypic identification of mutans streptococci from humans. Oral Micriobiol Immunol. 1998;13:17-22.

Li Y, Navia JN, Bian JY. Caries experience in deciduous dentition of rural Chinese children 3-5 years old in relation to the presence or absence of enamel hypoplasia. Caries Res. 1996;30:8-15.

Li Y, Caufield PW. The fidelity of initial acquisition of mutans streptococci by infants from their mothers. J. Dent. Res. 1995;74:681-685.

Li Y, Navia JN, Bian JY. Prevalence and distribution of developmental enamel defects in deciduous dentition of Chinese children 3 to 5 years old. Community Dent. Oral Epidemiol. 1995;23:72-79.

Li Y, Navia JN, Caufield PW. Colonization by mutans streptococci in the mouths of 3- and 4-year-old Chinese children with or without enamel hypoplasia. Archs. Oral Biol. 1994;39:1057-1062.