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Informative References

American Veterinary Medical Association (AVMA) Panel on Euthanasia
This publication contains the report of the AVMA panel covering all acceptable methods of euthanasia. Conditionally acceptable methods (those that may be used only under special conditions) are discussed as well. This document is the required standard for the selection of a method for euthanasia.

Special Report on Controlled Water and Food Access - Journal of Neuroscience Methods
This special report provides practical guidance on refinement of the use of food and fluid control as motivational tools for macaques used in behavioral neuroscience research.

National Association for Biomedical Research (NABR) presentation on the "Age of Enforcement"
This presentation is to review the changes being made by the USDA during the inspection process. The action plan can be found at and it indicates that the inspection and enforcement process will shift from its heretofore education focus to an enforcement focus. This shift could have a significant impact on the inspection process for research facilities. The focus has historically been on education, whereby the inspectors work with the institutions and their IACUCs to assure the welfare of the animals in each unique registered research facility. It now appears to be a more rigidly interpreted enforcement approach.

Roles of NIH Scientific Review Groups and IACUCs in Animal Research
This notice is to clarify how the Vertebrate Animal Section (VAS) of applications for grants, fellowships, and cooperative agreements is evaluated as part of the NIH peer review process and is considered as part of the overall scoring. Further clarification is provided on the oversight role of the Institutional Animal Care and Use Committee (IACUC) and review responsibility of NIH Scientific Review Groups (SRG).

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