Grant Application Form PHS 2590 (Revised November 2007)
See the list of required forms (includes OSP-customized forms).
NIH has revised the PHS 2590 application kit (11/07) for the Non-Competing Continuation Progress Report. It must be used for receipt dates of March 1, 2008 and thereafter. The online versions of the forms are available through the links provided below. Additional information and guidance is available from the Office of Sponsored Programs (OSP) Projects Officers.
The PHS 2590 and these instructions apply to the following grant mechanisms: RO1, RO3, R13, R15, R18, R21, R24, R25, R37, R42, R44, all K series, as well as the T32 (institutional training) grant. Program or grants management staff may require additional information, in which case they will notify the Principal Investigator and/or OSP. Specific instructions for the last two award types are included in the full kit.
We strongly recommend that investigators familiarize themselves with the complete instructions, forms, and policies contained in the PHS 2590 kit.
Quick Links to Content
- Required Forms
- Proposal Mechanics
- Sections of the Proposal
- Submission Procedures
Grant Progress Reports must be submitted two months before the beginning date of the next budget period. Unless advised otherwise in the notice of grant award (NGA), non-competing continuations are submitted using the Streamlined Noncompeting Award Process (SNAP).
Links are provided below to all required forms and formats in Rich Text Format (rtf). These files can be opened in any version Microsoft Word 95, 97, 2000 or XP. The face page has been specifically tailored for NYU submission. Computer-generated facsimiles of all other forms/formats may be substituted; however, they must maintain the exact wording and format, and (in the case of forms) include all captions and spacing.
- Form Page 1: Face Page (OSP-customized)
- Form Page 1 - continued: Additional form if Multiple PIs are proposed
- Form Page 2: Detailed Budget for Next Budget Period
- Form Page 3: Budget Justification
- Biographical Sketch
- Form Page 5: Progress Report Summary
- Form Page 6: Checklist (OSP-customized)
- Form Page 7: Personnel
- Continuation Page
- Targeted/Planned Enrollment Format Page
- Enrollment Report Format Page
- Other Support Format Page: Example
Deviations from font size specifications and page limitations will be grounds for PHS to reject and return the entire application without peer review. NIH now specifies the use of Ariel, Helvetica, Palatino Linotype, or Georgia typeface and a font size of 11 points or larger. No other font types/sizes will be accepted.
- Aside from those forms which have been preset with a smaller font, type size must meet the above specifications that allow no more than 15 characters per linear inch and no more than six lines per vertical inch.
- Margins should be at least a half-inch on all four sides.
- While a separate budget is not required by NIH unless there is a significant change, as discussed below, an updated budget (on form page 2) is required for University approval.
- In keeping with NIH instructions, non-competing budgets should request salary at rates of pay that DO NOT exceed the current legislatively imposed limit ($191,300 per year).
- Levels of effort should be calculated by person months (calendar, academic and summer).
- Do not number this page.
- This is a standard format required only for new senior/key personnel (four-page limit per person) that now requests a list of selected or ongoing (during the last three years) research projects.
- This form should also be completed for all new “Other Significant Contributors.”
- The progress report itself (exclusive of responses to the questions below) is limited to two pages excluding tables and/or figures that summarize key accomplishments, a list of publications, and the Inclusion Enrollment Report (if research involves the use of human subjects).
- You must insert answers to the following three questions at the beginning of the Progress Report Summary. Use blank pages to begin the Progress Report if inadequate space remains on form page 5.
- Has there been a change in Other Support of senior/key personnel since the last reporting period?
- Change refers to active support only (termination of a previously active grant, funding of a previously pending proposal).
- If yes, you are required to submit complete Other Support information (in the format shown on Form Page GG in the PHS 398 kit) only for the PI and key individuals.
- If no, so state.
- Will there be a significant change in level of effort for personnel named in the Notice of Grant Award (NGA) from what was approved for this project?
- Normally this applies only to the PI.
- A significant change in level of effort is defined as a 25% reduction in an individual's percentage of time originally committed to the project. This requirement applies regardless of whether or not the person is compensated from the grant. For example, if a key person on the project is expected to reduce his/her effort from 40% to 30%, this represents a 25% reduction in level of effort.
- If yes, explain.
- If no, so state.
- Is it anticipated that an estimated unobligated balance (including prior-year carryover) will be greater than 25% of the current year's total budget?
- Any estimated unobligated balance (including prior-year carryover) that is greater than 25% of the current year's total budget must be explained here. The explanation should include the reason for the significant balance and detail how it will be spent if carried forward into the next budget period.
- If none, so state.
- Progress Report. Discuss:
- Specific Aims. The aims, as actually funded, may differ in scope from those stated in the original, competing application. If they have not been modified, state this. If they have been modified, give the revised aims and the reason for the modification.
- Studies and Results. Describe these as they relate to the specific aims during the current budget year. If applicable, include a separate section(s) describing the results obtained by individuals supported on this grant through supplements.
- Supplements. If applicable, include a separate section(s) describing the results obtained by individuals supported on this grant through various supplements.
- Significance. Include a statement on the significance of findings to the scientific field and their potential impact on health.
- Plans. Summarize plans for the next year, including any important modifications to the original plans. Check “no change” on the summary page if the protocols are the same as the previous submission. Check “change” if the research involves the use of human subjects and/or vertebrate animals and the protocols are different.
- If your project involves human subjects, you must report the annual cumulative enrollment of subjects and their distribution by sex/gender and ethnicity/race, unless otherwise notified by your program official. Use the Inclusion Enrollment Report form. Please see detailed instructions and frequently asked questions at: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-01-053.html.
- If there are changes to the Targeted Enrollment, submit a revised form (see http://grants1.nih.gov/grants/funding/2590/enrollment.doc or http://grants1.nih.gov/grants/funding/2590/enrollment.pdf.
- Publications. For each publication not previously submitted to the awarding component, provide a link to a publicly available on-line journal or the NIH PubMed Central (PMC) submission identification number. One copy of the publication may be provided if an on-line link or PMC number is not yet available. List the complete citation of all publications resulting directly from the grant and not previously reported (not included in the 2-page limit). Submit only one copy of each publication to the awarding component. Applicants may ONLY include manuscripts that have been submitted or accepted for publication. If none, so state.
- Project-Generated Resources. If the research supported by this grant resulted in data, research materials (e.g., cell lines, DNA probes, animal models), protocols, software, or other information, e.g., inventions, available to be shared with other investigators, describe the resource and how it may be accessed.
- Do not number this page.
- List all key personnel, who participated in the project during the current budget period. These are individuals who are named as senior/key personnel in the Notice of Grant Award (NGA).
- Do not include “Other Significant Contributors” unless their involvement has changed so that they now meet the definition of senior/key personnel.
- Use only the last four digits of any social security numbers.
- Secure the application (only the signed original must be submitted) with rubber bands or paper clips only. DO NOT STAPLE COPIES.
- To ensure timely institutional review, PIs should submit completed application to OSP at least 10 working days in advance of the PHS deadline. Although OSP uses a courier service for the delivery of proposals, we cannot guarantee overnight delivery where this is required.
- Deliver one copy of the application, along with the OSP Synopsis form, signed by PI and Department Chair, to Dean's Office. OSP cannot submit a proposal without dean's approval.
- Deliver the original plus one agency copy to OSP. Include a copy of the synopsis form.
- The Authorizing Official at OSP reviews and signs proposal after receiving Dean’s approval, then transmits the application to PHS.
- The application package is sent to the Division of Extramural Activities Support, OER, National Institutes of Health, 6705 Rockledge Drive, Room 2207, MSC 7987, Bethesda, MD 20892-7987 (US Mail) or Bethesda, MD 20817 (for courier delivery).