Publication List of Yingkai Zhang

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39.  Z. Ke, Y. Zhou, P. Hu, S. Wang, D. Xie and Y. Zhang, J. Phys. Chem. B, ASAP. ( Cover Article)
Active Site Cysteine Is Protonated in the PAD4 Michaelis Complex: Evidence from Born-Oppenheimer Ab Initio QM/MM Molecular Dynamics Simulations

38.  L. Wang,  S. Broyde and Y. Zhang J. Mol. Biol.389, 787-796 (2009).
Polymerase-tailored variations in the Water-Mediated and Substrate-Assisted Mechanism for Nucleotidyl Transfer: Insights from a Study of T7 DNA Polymerase

37. H. Zheng, S. Wang and  Y. Zhang, J. Comp. Chem., ASAP.
Increasing the Time Step with Mass Scaling in Born-Oppenheimer ab initio QM/MM Molecular Dynamics Simulations

36. P. Hu, S. Wang and Y. Zhang, J. Am. Chem. Soc. , 130, 16721-16728 (2008).
A Highly Dissociative and Concerted Mechanism for the Nicotinamide Cleavage Reaction in Sir2Tm Enzyme Suggested by ab initio QM/MM Molecular Dynamics Simulations 

35. Z. Lu and Y. ZhangJ. Chem. Theory Comp., 4, 1237-1248 (2008).
Interfacing ab initio Quantum Mechanical Method with Classical Drude Osillator Polarizable Model for Molecular Dynamics Simulation of Chemical Reactions

34. H. Zheng and Y. ZhangJ. Chem. Phys. ,128, 204106 (2008).
Determination of Free Energy Profiles by Repository Based Adaptive Umbrella Sampling: Bridging Nonequilibrium and Quasiequilibrium Simulations

33. P. Hu, S. Wang and Y. Zhang, J. Am. Chem. Soc. , 130, 3806-3813 (2008).
How do SET-domain Protein Lysine Methyltransferases Achieve the Methylation State Specificity ? Revisited by ab initio QM/MM Molecular Dynamics Simulations.

32.  Z. Liu, A. W. Young, P. Hu,  A. J. Rice, C. Zhou, Y. Zhang and  N. R. Kallenbach, ChemBioChem , 8, 2063-2065 (2007).
Tuning Selectivity of Antimicrobial Peptides by Multivalent Design.

31. C. Xiao and Y. Zhang, J. Chem. Phys., 127, 124102 (2007).
Design-Atom Approach for the Quantum Mechanical/Molecular Mechanical Covalent Boundary: A Design-Carbon Atom with Five Valence Electrons.

30. C. Xiao and Y. Zhang, J. Phys. Chem. B ,  111, 6229-6235 (2007).
Catalytic Mechanism and Metal Specificity of Bacterial Peptide Deformylase: a Density Functional Theory QM/MM Study.

29. L. Wang, X. Yu, P. Hu, S. Broyde and Y. Zhang, J. Am. Chem. Soc. , 129, 4731-4737 (2007).
A Water-mediated and Substrate-assisted Catalytic Mechanism for Sulfolobus solfataricus  DNA Polymerase IV

28. S. Wang, P. Hu and Y. Zhang, J. Phys. Chem. B , 111, 3758-3764 (2007).
Ab initio Quantum Mechanical/Molecular Mechanical Molecular Dynamics Simulation of Enzyme Catalysis:
The Case of Histone Lysine Methyltransferase SET7/9

27. C. Corminboeuf, P. Hu, M. E. Tuckerman and Y. Zhang, J. Am. Chem. Soc. (Communication) , 128, 4530-4531 (2006).
Unexpected Deacetylation Mechanism Suggested by a Density Functional Theory QM/MM Study of Histone-Deacetylase-Like Protein

26.  P. Hu and Y. Zhang, J. Am. Chem. Soc. ,  128, 1272-1278  (2006).
 Catalytic Mechanism and Product Specificity of the Histone Lysine Methyltransferase SET7/9.  An  ab initio QM/MM-FE
Study with Multiple Initial Structures
.

25. Y. Cheng, Y. Zhang  and  J. A. McCammon, Protein Sci. , 15, 672-683 (2006).
How does Activation Loop Phosphorylation Modulate Catalytic Activity in the cAMP-dependent Protein Kinase:
A Theoretical Study.

24.  V. V. Karambelkar, C. Xiao, Y. Zhang, A. Sarjeant and D. P. Goldberg,  Inorg. Chem. , 45, 1409--1411  (2006).
Geometric Preferences in Iron(II) and Zinc(II) Model Complexes of Peptide Deformylase.

23. Y. ZhangTheor. Chem. Acc. , Special Issue of ``New Perspectives in Theoretical Chemistry'' , 116, 43-50 (2006).
Pseudobond ab initio QM/MM approach and its Applications to Enzyme Reactions.

22.  C. F. Wong, J. Kua, Y. Zhang, T. P. Straatsma and J. A. McCammon, Proteins, 61, 850-858 (2005).
Molecular Docking of Balanol to Dynamics Snapshots of Protein Kinase A.

21.  X. H. Chen, Y. Zhang,  J. Z.H. Zhang, J. Chem. Phys.122, 184105 (2005).
An efficient approach for ab initio energy calculation of biopolymers.

20.   Y. ZhangJ. Chem. Phys.122, 024114 (2005).
Improved Pseudobonds for Combined ab initio Quantum Mechanical/Molecular Mechanical (QM/MM) Methods.

19.  Y. Cheng, Y. Zhang, and J. A. McCammon, J. Am. Chem. Soc., .127, 1553 -1562 (2005).
 How Does the cAMP-Dependent Protein Kinase Catalyze the Phosphorylation Reaction: an  ab initio QM/MM Study 

18. A. M. Gao, D.W. Zhang, J. Z.H. Zhang and Y. Zhang , Chem. Phys. Lett., 394, 293-297 (2004).
An efficient linear scaling method for ab initio calculation of electron density of proteins.

17. J. Kua, Y. Zhang, A. C. Eslami, J. R. Butler, and J. A. McCammon, Protein Sci., 12, 2675-2684 (2003)
Studying the Roles of W86, E202, Y337 in Binding of Acetylcholine to Acetylcholinesterase using a Combined Molecular Dynamics and Multiple Docking Approach

16. G. A. Cisneros, H. Liu, Y. Zhang, and W. Yang, J. Am. Chem. Soc., 125, 10384-10393 (2003).
Ab Initio QM/MM Study Shows There Is No General Acid in the Reaction Catalyzed by 4-Oxalocrotonate Tautomerase

15. Y. Zhang, J. Kua and J. A. McCammon, J. Phys. Chem. B, 107, 4459-4463 (2003).
Influence of Structural Fluctuation on Enzyme Reaction Energy Barriers in Combined Quantum Mechanical/Molecular Mechanical Studies.

14. Y. Zhang and J. A. McCammon, J. Chem. Phys., 118, 1821-1827 (2003).
Studying the Affinity and Kinetics of Molecular Association with Molecular Dynamics Simulation.

13. Y. Zhang, J. Kua and J. A. McCammon, J. Am. Chem. Soc., 124, 10572-10577 (2002).
Role of the Catalytic Triad  and  Oxyanion Hole in Acetylcholinesterase Catalysis: An ab initio QM/MM Study.

12. J. Kua, Y. Zhang and J. A. McCammon, J. Am. Chem. Soc., 124, 8260-8267 (2002).
Studying Enzyme Binding Specificity in Acetylcholinesterase using a Combined Molecular Dynamics and Multiple Docking Approach.

11. Y. Zhang, H. Liu, and W. Yang, ``Ab initio qm/mm and free energy calculationsof enzyme reactions,''
in Computational Methods for Macromolecules -Challenges and Applications (T.~Schlick and H.~H. Gan, eds.), 332-354, Springer-Verlag, 2002.

10. Y. Zhang, H. Liu and W. Yang , J. Chem. Phys, 112, 3483-3492 (2000). Free energy calculations on enzyme reactions with an efficient iterative procedure to determine minimum energy paths on a combined ab initio QM/MM potential

9. H. Liu, Y. Zhang and W. Yang , J. Am. Chem. Soc. , 122, 6560-6570 (2000).
How is the active site of enolase organized to catalyze two different reaction steps?

8. W. Yang, Y. Zhang and P. W. Ayers, Phys. Rev. Lett., 84, 5172-5175 (2000).
Degenerate Ground States and a Fractional Number of Electrons in Density and Reduced Density Matrix Functional Theory,

7. Y. Zhang and W. Yang, Theore. Chem. Acc., 103, 346-348 (2000).
Perspective on ``Density-Functional Theory for Fractional Particle Number:Derivative Discontinuities of the Energy'' by J.P. Perdew, R.G. Parr,M. Levy and J.L. Balduz,Jr.

6. C. Enkvist, Y. Zhang and W. Yang, Int. J. Quan. Chem., 79, 325-329 (2000).
Density Functional Study of a Weakly Hydrogen Bonded Benzene-Ammonia Complex: the Importance of the Exchange Functional .

5. Y. Zhang, T. S. Lee and W. Yang, J. Chem. Phys., 110, 46-54 (1999).
A Pseudobond Approach to Combining Quantum Mechanical and Molecular Mechanical Methods.

4. Y. Zhang and W. Yang, J. Chem. Phys.,109, 2604-2608 (1998).
A Challenge for Density Functionals: Self-interaction Error Increases for Systems with a Noninteger Number of Electrons.

3. Y. Zhang and W. Yang, Phys. Rev. Lett., 80, 890 (1998).
Comment on "Generalized Gradient Approximation Made Simple" .

2. Y. Zhang, W. Pan and W. Yang, J. Chem. Phys., 107, 7921-7925 (1997).
Describing van der Waals Interactions in Diatomic Molecules with Generalized Gradient Approximations: the role of the Exchange Functional .

1. Y. Zhang, G. Wang and Y. Jiang, J. of Nanjing Univ. (Natural Science Edition), 29, 400-406 (1993).
Application of the Faraday Effect in Chemistry.


Last modified:  June 9, 2009