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Publications

Shah, N.H.; Kirshenbaum, K. (2008). Direct Generation of Polymer Films on Copper Surfaces Through Azide-Alkyne Cycloaddition Reactions Between Peptidomimetic Oligomers. Macromol. Rapid Commun. 29: 1134-1139. HTML / PDF

Shah, N.H.; Kirshenbaum, K. (2008). Photoresponsive Peptoid Oligomers Bearing Azobenzene Side Chains. Org. Biomol. Chem. 6: 2516-2521. HTML / PDF

Maayan, G.; Yoo, B.; Kirshenbaum, K. (2008). Heterocyclic Amines for the Construction of Peptoid Oligomers Bearing Multi-Dentate Ligands. Tet. Lett. 49: 335-338. HTML / PDF

Shin, S.-B.Y.; Kirshenbaum, K. (2007). Conformational Rearrangements by Water-Soluble Peptoid Foldamers. Org. Lett. 9: 5003-5006. HTML / PDF

Holub, J. M., Garabedian, M.J., Kirshenbaum, K. (2007). Peptoids on Steroids: Precise Multivalent Estradiol-Peptidomimetic Conjugates Generated via Azide-Alkyne [3+2] Cycloaddition Reactions. QSAR & Comb. Sci. 26: 1175-1180. PDF

Holub, J.M., Jang, H., Kirshenbaum, K. (2007). Fit To Be Tied: Conformation-Directed Macrocyclization of Peptoid Foldamers. Org. Lett. 9: 3275-3278. HTML / PDF

Shin, S.-B.Y., Yoo, B., Todaro, L., Kirshenbaum, K. (2007). Cyclic Peptoids. J. Am. Chem. Soc. 129: 3218-3225. HTML / PDF

Fafarman, A.T., Borbat, P.P., Freed, J.H., Kirshenbaum, K. (2007). Characterizing the structure and dynamics of folded oligomers: Pulsed ESR studies of peptoid helices. Chem. Commun. 2: 377-379. HTML / PDF

Utku, Y., Dehan, E., Ouerfelli, O., Piano, F., Zuckermann, R.N., Pagano, M., Kirshenbaum, K. (2006). A peptidomimetic siRNA transfection reagent for highly effective gene silencing. Mol. BioSystems. 2: 312-317. HTML / PDF

Spencer, T., Yoo, B., Kirshenbaum, K. (2006). Purification and modification of fullerene C60 in the undergraduate laboratory. J. Chem. Ed. 83: 1218-1220. PDF

Anderson, E.A., Isaacman, S., Peabody, D.S., Wang, E.Y., Canary, J.W., Kirshenbaum, K. (2006). Viral nanoparticles donning a paramagnetic coat: conjugation of MRI contrast agents to the MS2 capsid. NanoLetters. 6: 1160-1164. HTML / PDF

Holub, J.M., Jang, H., Kirshenbaum, K. (2006). Clickity-click: Highly functionalized peptoid oligomers generated by sequential conjugation reactions on solid-phase support. Org. Biomol. Chem. 4: 1497-1502. HTML / PDF

Huang, K., Wu, C.W., Sanborn, T.J., Patch, J.A., Kirshenbaum, K., Zuckermann, R.N., Barron, A.E., Radhakrishnan, I. (2006). A threaded loop conformation adopted by a family of peptoid nonamers. J. Am. Chem. Soc. 128: 1733-1738. HTML / PDF

Yoo, B., Kirshenbaum, K. (2005). Protease-mediated ligation of abiotic oligomers. J. Am. Chem. Soc. 127: 17132-17133. HTML / PDF

Jang, H.J., Fafarman, A., Holub, J.M., Kirshenbaum, K. (2005). Click to fit: Versatile polyvalent display on a peptidomimetic scaffold. Org. Let. 7: 1951-1954. HTML / PDF

Arora, P.S., Kirshenbaum, K. (2004). Nano-tailoring: Stitching alterations on viral coats. Chem. Biol. 11: 418-420. HTML / PDF

Book Chapters

Patch, J.A., Kirshenbaum, K., Seurynck, S.L., Zuckermann, R.N., Barron, A.E. “Versatile Oligo(N-substituted) Glycines: The Many Roles of Peptoids in Drug Discovery”, invited chapter in Pseudo-peptides in Drug Development; Nielsen, P.E., Ed.; Wiley-VCH, Weinheim, Germany, 2004.

Prior Publications

Wu, C.W., Kirshenbaum, K., Sanborn, T.J., Patch, J.A., Huang, K., Dill, K.A., Zuckermann, R.N., Barron, A.E. (2003). Structural and spectroscopic studies of peptoid oligomers with a-chiral aliphatic side chains. J. Am. Chem. Soc. 125: 13525-13530. HTML / PDF

Kwon, I., Kirshenbaum, K., Tirrell, D.A. (2003). Breaking the degeneracy of the genetic code. J. Am. Chem. Soc. 125: 7512-7513. HTML / PDF

Kirshenbaum, K., Carrico, I.S., Tirrell, D.A. (2002). Biosynthesis of proteins incorporating a versatile set of phenylalanine analogs. ChemBioChem 3: 235-237. HTML / PDF

Kirshenbaum, K., Zuckermann, R.N., Dill, K.A. (1999). Designing polymers that mimic biomolecules. Curr. Opin. Struc. Biol. 9: 530-535. PDF

Kirshenbaum, K., Young, M., Highsmith, S. (1999). Predicting allosteric switches in myosins. Protein Sci. 8: 1806-1815. PDF

Young, M., Kirshenbaum, K., Dill, K.A., Highsmith, S. (1999). Predicting conformational switches in proteins. Protein Sci. 8: 1752-1764. PDF

Armand, P., Kirshenbaum, K., Goldsmith, R.A., Farr-Jones, S., Barron, A.E., Truong, K.T.V., Dill, K.A., Mierke, D.F., Cohen, F.E., Zuckermann, R.N., Bradley, E.K.. (1998). NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains. Proc. Natl. Acad. Sci. USA 95: 4309-4314. HTML / PDF

Kirshenbaum, K., Barron, A.E., Goldsmith, R.A., Armand, P., Bradley, E.K., Truong, K.T.V., Dill, K.A., Cohen, F.E., Zuckermann, R.N. (1998). Sequence-specific polypeptoids: A diverse family of heteropolymers with stable secondary structure. Proc. Natl. Acad. Sci. USA 95: 4303-4308. HTML / PDF

Armand, P., Kirshenbaum, K., Falicov, A., Dunbrack, R.L., Dill, K.A., Zuckermann, R.N., Cohen, F.E. (1997). Chiral N-substituted glycines can form stable helical conformations. Folding & Design 2: 369-375. HTML / PDF

Kirshenbaum, K., Daggett, V. (1995). Sequence effects on conformational properties of the Amyloid b(1-28) Peptide: Testing a proposed mechanism for the aàb transition. Biochemistry 34: 7640-7647. PDF

Kirshenbaum, K., Daggett, V. (1995). pH-Dependent conformations of the amyloid b(1-28) peptide fragment explored using molecular dynamics. Biochemistry 34: 7629-7639. PDF

Kirshenbaum, K., Papp, S., Highsmith, S. (1993). Cross-linking myosin subfragment 1 Cys-697 and Cys-707 modifies ATP and actin binding site interactions. Biophys. J. 65: 1121-1129. HTML (Abstract Only)