Ph.D. (08/2006), Biophysical Chemistry, 

New York University, New York, NY. Dissertation: “ Nucleotide excision repair and translesion synthesis study of equine derived 4-OHEN DNA adducts.”

 

M.S. (07/2001), Analytical Chemistry, 

Fudan University, Shanghai, P.R.China. Dissertatiion: “Study of sol-gel based H2O2 and glucose biosensors.”

 

B.S. (07/1998), Chemistry, 

Fudan University, Shanghai, P.R.China

 

SKILLS

Four years experience in the field of DNA repair of the damaged DNA mutations and translesion DNA synthesis by the novel bypass polymerases. 
Synthesis and characterization of site-specifically modified DNA sequences (oligonucleotidesoligos).
Expert in thermodynamics, PAGE analysis, radioactive isotope labeling, enzymatics (UvrABC system and human repair enzymes; polymerases).
Extensive experience with HPLC, NMR, Uv-vis, CD, MALDY-TOF mass spectrometry, fluorescence and absorption spectroscopy.

EXPERIENCE

2001- present 

    New York University, New York, NY (Supervisor: Nicholas E. Geacintov)

·        Synthesis and characterization of estrogen derivatives 4-OHEN DNA adducts

·        Thermodynamics of unmodified and modified oligos

·        Nucleotide excision repair of benzo[a]pyrene and estrogen 4-OHEN adducts using UvrABC system and human repair proteins

·        DNA replication and kinetics study of 4-OHEN adducts using A- and Y-family polymerses

·        Interaction of UvrA, UvrB proteins and DNA adducts

·        Supervised two new graduate students and one undergraduate student

 

1994-2001 

    Fudan University, Shanghai, P. R. China (Supervisor: Jilie Kong)

·        Development of Al2O3 based H2O2 biosensor employing horseradish peroxidase and catalase

·        Development of a nanoporous ZrO2 matrix based amperometric biosensor

·        A BOD biosensor based on a microorganism immobilized on a nano matrix

HOBBIES

    Music, reading, watching movies and sleep.

 

Recent Publications Projects Digital Analysis of

    Gel Images

 Instrumentation