Population trends and distribution of genetic variation in western lowland gorillas: Implications for conservation

E. Jean Wickings,1 Nicola M. Anthony,2 Mireille Bawe-Johnson,1 Stephen L. Clifford,1 Kate A. Abernethy,1 Fiona Maisels,3 and Michael W. Bruford4

1Unité de Génétique des Ecosystèmes Tropicaux, Centre International de Recherches Medicales de Franceville (CIRMF), Gabon, 2School of Biological Sciences, University of New Orleans, 3WCS-Gabon, Libreville, Gabon, 4School of Biosciences, Cardiff University, United Kingdom

Abstract

In addition to the historical pressures of hunting and habitat fragmentation, current gorilla populations are under intense local risk of extinction from haemorrhagic viral fever (Ebola). Recent estimates have shown drastic declines of up to 50% of the total population, with local losses of up to 90%. Estimates of genetic variability using mitochondrial sequences from the hypervariable region (HV-1) of the D-loop in western lowland gorillas reveal a high genetic diversity and a complex historical genetic structure that may be tied to ice age changes in tropical forest cover.

After removing nuclear translocations and recombinant sequence artefacts, two geographically defined and highly divergent haplogroups (C, D) are found in western lowland gorillas and each of these is further subdivided into subgroups (C1, C2, D1-3). The northern-most haplogroup C (Nigeria, Cameroon and northern Gabon) shows the highest overall diversity, with similar haplotypes (C1) found in Cross River, Ebo Forest and Lobeke gorillas. Gene flow occurs across the Sanaga River, whereas the Sangha River separates C2 (Dja, Cameroon and north-east Gabon) and D2 (Central African Republic, CAR) subgroups. Haplogroup D is less variable although widely distributed from Equatorial Guinea and Monts de Cristal, Gabon (D1), CAR (D2) and southern and central Gabon and Congo (D3). The least variable subgroup (D3), comprising relatively few, closely related haplotypes, dominates the southern part of the western lowland gorilla range. Gorillas in north-eastern Gabon show a mixture of haplotypes (C2, D2 and D3).

Disease progression models imply recent passage of Ebola through areas of current low gorilla density in south-eastern Cameroon, northen Gabon and central Congo, avoiding the Sangha-Dzanga Triangle where ape densities remain high. Conservation efforts should focus not only on areas of current high gorilla density or distinct genetic composition, but also on areas where Ebola has decimated populations, to monitor their recovery and residual genetic variability. Thus we highlight the need for additional resources for re-surveying “Ebola affected” areas and continuing genetic monitoring of their great ape populations.