Molecular systematics of the primates: What we've learned, where we need go

Todd Disotell1,2

1Center for the Study of Human Origins, Department of Anthropology, New York University, 2New York Consortium in Evolutionary Primatology (NYCEP)

Abstract

Molecular data collected over the last three decades has dramatically shaped our understanding of the Order Primates. The entire genomes of humans, chimpanzees, and rhesus macaques have now been sequenced with the sequencing of additional taxa under way or planned for the near future. Technical advances allow us to determine DNA sequences and to characterize genetic markers such as microsatellites, SINES, LINES, and SNPs more efficiently and from non-invasively collected samples including hair, feces, skins, bones, and museum specimens. Analytical models based upon parsimony, likelihood, and Bayesian approaches have been developed that take into account both theoretical advances in the field and empirically tested models of molecular evolution. Techniques to infer molecular divergence date estimates with associated errors have been developed and applied even to lineages that are undergoing different rates of molecular evolution. These advances have been particularly informative in studying human, ape, and Old World monkey phylogeny, population genetics, and molecular evolution. However, many gaps still exist in our investigations of New World monkeys, tarsiers, lemurids, and lorisids, though the broad outlines of their phylogenetic history are better understood. Molecular analyses will continue to provide major contributions to our knowledge of primate evolutionary history, taxonomy, and conservation.