NYU: DoC: The Arora Group: Publications

Henchey, L. K.; Kushal, S.; Dubey, R.; Chapman, R. N.; Olenyuk, B. Z.; Arora, P. S. "Inhibition of Hypoxia Inducible Factor 1–Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix." J. Am. Chem. Soc. 2010, 132, 941-943.[PDF]

Jochim, A. L.; Miller, S. E.; Angelo, N. G.; Arora, P. S. “Evaluation of triazolamers as active site inhibitors of HIV-1 protease.” Bioorg. Med. Chem. Lett. 2009, 19, 6023-6026.[PDF]

Arora, P.S.; Ansari, A. Z. “A Notch above other inhibitors.” Nature 2009, 462, 171-172.[PDF]

Guarracino, D. A.; Arora, P. S. “Making Strides in Peptide-Based Therapeutics.” Chem. Biol. 2009, 16, 919-920.[PDF ]

Jochim, A. L.; Arora, P. S. “Assessment of helical interfaces in protein-protein interactions.” Mol. BioSyst. 2009, 5, 924-926.[PDF]

Bu, J.; Dong, X. Y.; Zhang, J. Z. H.; Arora, P. S. “Dynamical Binding of Hydrogen-Bond Surrogate Derived Bak Helices to Antiapoptotic Protein Bcl-xL 2.” J. Phys Chem. B 2009, 113, 3565–3571.[PDF]

Patgiri, A.; Jochim, A. L.; Arora, P. S. "A Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences in Alpha-Helical Conformation." Acc. Chem. Res. 2008, 41, 1289-1300.[PDF]

Henchey, L. K.; Jochim, A. L.; Arora, P. S. “ Contemporary Strategies for the Stabilization of Peptides in the Alpha-Helical Conformation” Curr. Opin. Chem. Biol. 2008, 12, 692-697.[PDF]

Kirshenbaum, K.; Arora, P. S. “Cross-dressing proteins by olefin metathesis” Nature Chem. Biol.2008, 4, 527-528.[PDF]

Chapman, R. N.; Kulp, J. L. III; Patgiri, A.; Kallenbach, N. R.; Bracken, C.; Arora, P. S. “Trapping a Folding Intermediate of the Alpha-Helix: Stabilization of the Pi-Helix.” Biochemistry (Accelerated Publication)2008, 47, 4189-4195.[PDF]

Liu, J.; Wang, D.; Zheng, Q.; Lu, M.; Arora, P. S. “Atomic Structure of a Short Alpha-Helix Stabilized by a Main Chain Hydrogen Bond Surrogate”. J. Am. Chem. Soc. 2008, 130, 4334-4337.[PDF]

Wang, D.; Lu, M.; Arora, P.S. “Inhibition of HIV-1 Fusion by Hydrogen-Bond Surrogate Based Alpha-Helices.” Angew. Chem. Int. Ed. 2008, 47, 1879-1882.[PDF]

Angelo, N.; Arora, P. S. “Solution and Solid Phase Synthesis of Triazole Oligomers that Display Protein-like Functionality.” J. Org. Chem. 2007, 72, 7963-7967. [PDF]

Angelo, N.; Henchey, L. K.; Waxman, A. J.; Wink, D.; Canary, J. C.; Arora, P. S. “Synthesis and Characterization of Aldol Condensation Products from Unknown Aldehydes and Ketones: An Inquiry-Based Experiment in the Undergraduate Laboratory.” J. Chem. Educ. 2007, 84, 1816-1818. [PDF]

Chapman, R. N.; Arora, P. S. "Optimized Synthesis of Hydrogen-Bond Surrogate Helices: Surprising Effects of Microwave Heating on the Activity of Grubbs Catalysts." Org. Lett. 2006, 8, 5825-5828. [PDF]

Angelo, N. G.; Arora, P. S. "Nonpeptidic Foldamers from Amino Acids: Synthesis and Characterization of 1,3-Substituted Triazole Oligomers." J. Am. Chem. Soc. 2005, 127, 17134-17135. [PDF]

Wang, D.; Liao, W.; Arora, P. S. "Enhanced Metabolic Stability and Protein-Binding Properties of Artificial Alpha-Helices Derived from a Hydrogen-Bond Surrogate: Application to Bcl-xL." Angew. Chem. Int. Ed. 2005, 44, 6525-6529. [PDF]

Dimartino, G.; Wang, D.; Chapman, R.N.; Arora, P. S. "Solid-Phase Synthesis of Hydrogen-Bond Surrogate-Derived Alpha-Helices." Org. Lett. 2005, 7, 2389-2392. [PDF]

Arora, P. S. "Adding Specificity to Artificial Transcription Factors." Chem. Biol. 2005, 12, 262-263. [PDF]

Arora, P. S.; Kirshenbaum, K. "Nano-Tailoring: Stitching Alterations on Viral Coats." Chem. Biol. 2004, 11, 418-420. [PDF]

Eisenfuhr, A.; Arora, P.S.; Sengle, G.; Nowick, J.S.; Famulok, M. "A Ribozyme with 1,4-Michaelase Activity: Synthesis of the Substrate Precursors." Bioorg. Med. Chem. 2003, 11, 235-249.

Arora, P.S.; Ansari, A.Z.; Best, T.P.; Ptashne, M.; Dervan, P.B. "Design of Artificial Transcriptional Activators with Rigid Poly-L-proline Linkers." J. Am. Chem. Soc. 2002, 124, 13067-13071.

Belitsky, J.M.; Arora, P.S.; Beerman, T.; Dervan, P.B. "Cellular uptake of polyamide-dye conjugates." Bioorg. Med. Chem. 2002, 10, 3313-3318.

Sengle, G.; Eisenfuhr, A.; Arora, P.S.; Nowick, J.S.; Famulok, M. "Novel RNA catalysts for the Michael reaction." Chem. Biol. 2001, 5, 459-473.

Sengle, G.; Jenne, A.; Arora, P. S.; Seelig, B.; Nowick, J. S.; Jaschke, A.; Famulok, M. "Synthesis, incorporation efficiency, and stability of disulfide bridged functional groups at RNA 5'-ends." Bioorg. Med. Chem. 2000, 8, 1317-29.

Arora, P. S.; Van, Q. N.; Famulok, M.; Shaka, A. J.; Nowick, J. S. "Design and synthesis of a transition state analogue for the Diels-Alder reaction." Bioorg. Med. Chem. 1998, 6,1421-28.

Benson, S.C.; Arora, P.S.; Glazer, A. N. "Heterodimeric DNA-binding dyes designed for energy transfer: synthesis and spectroscopic properties." Nucleic Acids Res. 1993, 21, 5727-35.