Drugs for the Future:
By the time
many of today's students enter the workforce, career opportunities
will have radically changed. In April of 2003 the Human
Genome Project culminated in the completion of the full human
genome. The National Human Genome Research Institute now must
move forward into the genomic era with research aimed at improving
human health and fighting disease.
modeling scientists will be better able to design new and more
potent drugs against diseases such as Cancer, AIDS, and Arthritis.
to the Left: The 3D structure of a protein drug target. Using
the crystallographic structure fo a protein, Syrrx (a drug
design company) used computational methods to design a small
molecule drug (shown in green) that can inhibit the disease-causing
activity of the protein.
modeling not only has the potential to bring new drugs to the
market, but a vast array of new materials. The discovery of fullerenes,
view the BuckyTube in 3-D click here]
superconducting cuprates (as well as other complex inorganic compounds),
are expected to produce new materials in the optics, ceramic,
semiconductor and biomaterials markets.
5K Image In addition, recent structural
determination of vital photosynthetic proteins will lead the way
to artificial photosynthesis.