Associate Professor of Orthodontics and Basic Science & Craniofacial Biology
DDS 1992, University of Porto, Portugal; MS in Oral Biology 1997, University of Pennsylvania; DMD 2001, University of Pennsylvania; PhD in Developmental Biology 2001, University of Pennsylvania
Research Interests: Physiology of growth plate cartilage as a platform for a new approach to tissue engineering of bone • Cell and molecular biology of growth plate chondrocyte differentiation, maturation, and apoptosis • Role of nitric oxide in Pi-induced apoptosis in chondrocytes • Function of NO in chondrogenesis
S. M. Oliveira, D. Q. Mijares, G. Turner, I. F. Amaral, M. A. Barbosa, and C. C. Teixeira. Engineering endochondral bone: in vivo studies. Tissue engineering. Part A. 15(3):635-43, 2009 Mar.
C. C Teixeira, H. Agoston, and F. Beier, Nitric Oxide, C-type Natriuretic Peptide and cGMP as Regulators of Cartilage Development. Developmental Biology (2008) 319: 171-178.
C. C. Teixeira, A. P. Padron, and Y. Nemelivsky, Apoptosis of growth plate chondrocytes occurs through a mitochondrial pathway. The Angle Orthodontist (2007) 77(1): 129–134.
C. C. Teixeira, A. P. Padron, and Y. Nemelivsky, Apoptosis of growth plate chondrocytes occurs through a mitochondrial pathway. The Angle Orthodontist (2006) 77 (1): 129–134.
Cristina C. Teixeira, Yelena Nemelivsky, Claudia Karkia, Racquel Z. Legeros. Biphasic Calcium Phosphate: A Scaffold for Growth Plate Chondrocyte Maturation. Tissue Engineering. 2006, 12(8): 2283-2289.
C. C. Teixeira, H. Ischiropoulos, P. Leboy, and I. M Shapiro, Nitric Oxide-Nitric Oxide Synthase Regulates Key Maturational Events During Chondrocyte Terminal Differentiation, Bone (2005) 37:37-45
Cristina C. Teixeira, Ramesh Rajpurohit, Kyle Mansfield, Cameron J. Koch and Irving Shapiro, Maturation Dependent Thiol Loss Increases Susceptibility to Apoptosis, J Bone and Min Res (2003) 18(4):662-668.
C. S. Adams, K. D. Mansfield, R. Rajpurohit, H. Tachibana, C.C. Teixeira and I. M. Shapiro, Components of the Cartilage Extracellular Matrix Regulate Chondrocyte Apoptosis. In: Shapiro IM, Handerson, HC, Boyan B(ed) The Growth Plate (2002), IOS Press, Amsterdam.
Cristina C. Teixeira, Kyle Mansfield, Caryn Hertkorn, Harry Ischiropoulos, Irving M. Shapiro, Pi-induced Chondrocyte Apoptosis is Linked to Nitric Oxide Generation, American J of Physiology (2001) 281: C833-C839.
Cristina C. Teixeira, New horizons in understanding early tooth development, Clinical Orthodontics and Research, (1999) 2:171-174.
Shapiro, K. Mansfield, Z. Tao, K. Ohyama, C Teixeira, C Chung, C Koch, R Rajpurohit, Oxygen Regulation of Chondrocyte Function: Reevaluation of the Hypothesis that Cells in the Growth Plate are Hypoxic. In Skeletal Growth and Development: Clinical Issues and Basic Science Advancements, (1998) by the American Academy of Orthopedic Surgeons (First Edition).
C. C. Teixeira, I.M. Shapiro, M. Hatori, R. Rajpurohit and C. J. Koch, Retinoic Acid Modulation of Glutathione and Cysteine Metabolism in Chondrocytes, BiochemJ (1996) 314:21-26.
Ramesh Rajpurohit, Cameron J. Koch, Zhuliang Tao, Cristina C Teixeira, and Irving Shapiro, Adaptation of Chondrocytes to Low Oxygen Tension: Relationship Between Hypoxia and Cellular Metabolism, J of Cellular Physiology (1996) 168:424-432.
Teixeira, M. Hatori, P. S. Leboy, M. Pacifici, I. M. Shapiro, A Rapid and Ultrasensitive Method For Measurement of DNA, Calcium and Protein Content, and Alkaline Phosphatase Activity of Chondrocyte Cultures, Calcif Tissue Int (1995) 56:252-256.
M. Hatori, J. Sparkman, C. C. Teixeira, M. Grynpas, J. Nervina, N. Olivieri, I. M: Shapiro, Effects of Deferoximine on Chondrocyte Alkaline Phosphatase Activity: Proxidant Role of Deferoximine in Thalassemia, Calcif Tissue Int (1995) 57: 229-236.