February 25, 2009
Presenter: Kurt Wong
Respondent: Magalí Armillas-Tiseyra
Mechanisms of malarial propogation
Malaria is a disease that kills nearly 1 million people every year. Why can't we produce a productive immune response, one that will kill the parasite and provide
immunity against re-infection? My lab proposes that the parasite turns off the immune response by altering the function of dendritic cells, which is the primary cell
type responsible for starting the immune response in the first place. My thesis project has been to understand how these dendritic cells are changing during malaria
infections, both using a mouse model and in humans.
the texts were:
Chapter 2: Vertebrate Immunology.
from
Frank, S.A. 2002. Immunology and Evolution of Infectious Disease. Princeton University Press.
and
Greenwood, B.M. et al. 2005. Malaria. Lancet, volume 365, pages 1487-1498.