Nate Traaseth Lab


Publications with NYU Affiliation

44. Kushal S, Lao BB, Henchey LK, Dubey R, Mesallati H, Traaseth NJ, Olenyuk BZ, Arora PS (2013) Protein Domain Mimetics as in vivo Modulators of Hypoxia-Inducible Factor Signaling. Proc Natl Acad Sci, 110, 15602-7. [pdf]

43. Gayen A, Banigan JR, Traaseth NJ (2013) Ligand-Induced Conformational Changes of the Multidrug Resistance Transporter EmrE Probed by Oriented Solid-State NMR Spectroscopy. Angew Chemie Int Ed, 52, 10321-4. [pdf]

*Featured on back-cover [link].

42. Chen H, Huang Z, Dutta K, Blais S, Neubert TA, Li X, Cowburn D, Traaseth NJ, Mohammadi M (2013) Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Pathogenic Gain-of-Function Mutations. Cell Reports, 4(2), 376-84.[pdf].

*F1000 Article Recommendation [link].

41. Banigan JR, Gayen A, Traaseth NJ (2013) Combination of 15N Reverse Labeling and Afterglow Spectroscopy for Assigning Membrane Protein Spectra by Magic-Angle-Spinning Solid-State NMR: Application to the Multidrug Resistance Protein EmrE. J Biomolec NMR, 55, 391-9.[pdf]

40. Banigan JR and Traaseth NJ (2012) Using Afterglow Magnetization from Cross-Polarization Magic-Angle-Spinning Solid-State NMR Spectroscopy to Obtain Simultaneous Heteronuclear Multidimensional Spectra. J Phys Chem B, 116, 7138-44.[pdf]

39. Traaseth NJ, Chao F.A., Masterson LR, Mangia S, Garwood M, Michaeli S, Seelig B, Veglia G (2012) Heteronuclear Adiabatic Relaxation Dispersion (HARD) for Quantitative Analysis of Conformational Dynamics in Proteins. J Magn Reson, 219, 75-82. [pdf]

38. Verardi R, Traaseth NJ, Masterson LR, Vostrikov VV, Veglia G. (2012) Isotope Labeling for Solution and Solid-state NMR Spectroscopy of Membrane Proteins. Adv Exp Med Biol, 992, 35-62. [pdf]


Publications from research prior to joining NYU

37. Gustavsson M, Verardi R, Mullen DG, Mote KR, Traaseth NJ, Gopinath T, Veglia G (2013) Allosteric Regulation of SERCA by Phosphorylation-Mediated Conformational Shift of Phospholamban. Proc Natl Acad Sci, 110, 17338-43. [pdf]

36. Gustavsson M, Traaseth NJ, Veglia G (2012) Probing Ground and Excited States of Phospholamban in Model and Native Lipid Membranes by Magic Angle Spinning NMR. Biochim Biophys Acta, 1818, 146-53. [pdf]

35. Gustavsson M, Traaseth NJ, Veglia G (2011) Activating and Deactivating Roles of Lipid Bilayers on the Ca2+-ATPase/Phospholamban Complex. Biochemistry, 50, 10367-74. [pdf]

34. Mote KR, Gopinath T, Traaseth NJ, Veglia G (2011) Multidimensional Oriented Solid-State NMR Experiments Enable the Sequential Assignment of Uniformly 15N Labeled Integral Membrane Proteins in Magnetically Aligned Lipid Bilayers. J Biomol NMR, 51, 339-46. [pdf]

33. Gaffarogullari EC, Masterson LR, Metcalfe EE, Traaseth NJ, Balatri E, Musa MM, Mullen D, Distefano MD, Veglia G (2011) A Myristoyl/Phosphoserine Switch Controls camp-Dependent Protein Kinase Association to Membranes. J Mol Biol, 411, 823-36. [pdf]

32. Verardi R, Shi L, Traaseth NJ, Walsh N, Veglia G (2011) Structural Topology of Phospholamban Pentamer in Lipid Bilayers by a Hybrid Solution and Solid-State NMR Method. Proc Natl Acad Sci, 108, 9101-6. [pdf]

31. Traaseth NJ, Veglia G (2011) Frequency-Selective Heteronuclear Dephasing and Selective Carbonyl Labeling to Deconvolute Crowded Spectra of Membrane Proteins by Magic Angle Spinning NMR. J Magn Reson, 211, 18-24. [pdf]

30. Gustavsson M, Traaseth NJ, Veglia G (2011) Lipid-Mediated Folding/Unfolding of Phospholamban as a Regulatory Mechanism for the Sarcoplasmic Reticulum Ca(2+)-ATPase. J Mol Biol, 408, 755-65. [pdf]

29. Shi L, Traaseth NJ, Verardi R, Gustavsson M, Gao J, Veglia G (2011) Paramagnetic-based NMR Restraints Lift Residual Dipolar Coupling Degeneracy in Multidomain Detergent-Solubilized Membrane Proteins. J Am Chem Soc, 133, 2232-41. [pdf]

28. Verardi R, Traaseth NJ, Shi L, Porcelli F, Monfregola L, De Luca S, Amodeo P, Veglia G, Scaloni A. (2011) Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers. Biochim Biophys Acta, 1808, 34-40. [pdf]

27. Traaseth NJ, Gopinath T, Veglia G (2010) On the Performance of Spin Diffusion Techniques in Oriented Solids: Prospects for Resonance Assignments and Distance Measurements from Separated Local Field Experiments. J Phys Chem B, 114, 13872-80. [pdf]

26. Veglia G, Ha KN, Shi L, Verardi R, Traaseth NJ (2010) What can we learn from a small regulatory membrane protein? Methods Mol Biol 654, 303-19. [pdf]

25. Mangia S*, Traaseth NJ*, Veglia G, Garwood M, Michaeli S. (2010) Probing slow protein dynamics by adiabatic R(1rho) and R(2rho) NMR experiments. J Am Chem Soc 132, 9979-81. [pdf] (*co-first author*)

24. Gopinath T, Verardi R, Traaseth NJ, Veglia G (2010) Sensitivity enhancement of separated local field experiments: application to membrane proteins. J Phys Chem B 114, 5089-95. [pdf]

23. Gopinath T, Traaseth NJ, Mote K, Veglia G. (2010) Sensitivity enhanced heteronuclear correlation spectroscopy in multidimensional solid-state NMR of oriented systems via chemical shift coherences. J Am Chem Soc 132, 5357-63. [pdf]

22. Haynes V, Traaseth NJ, Elfering S, Fujisawa Y, Giulivi C. (2010) Nitration of specific tyrosines in FoF1 ATP synthase and activity loss in aging. Am J Physiol Endocrinol Metab 298, E978-87. [pdf]

21. Traaseth NJ, Veglia G (2010) Probing excited states and activation energy for the integral membrane protein phospholamban by NMR CPMG relaxation dispersion experiments. Biochim Biophys Acta 1798, 77-81. [pdf]

20. Shi L, Traaseth NJ, Verardi R, Cembran A, Gao J, Veglia G. (2009) A refinement protocol to determine structure, topology, and depth of insertion of membrane proteins using hybrid solution and solid-state NMR restraints. J Biomol NMR 44, 195-205. [pdf]

19. Traaseth NJ, Shi L, Verardi R, Mullen DG, Barany G, Veglia G. (2009) Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach. Proc Natl Acad Sci 106, 10165-70. [pdf]

18. Deng Y, Wang Y, Holtz B, Li J, Traaseth N, Veglia G, Stottrup BJ, Elde R, Pei D, Guo A, Zhu XY (2008) Fluidic and air-stable supported lipid bilayer and cell-mimicking microarrays. J Am Chem Soc 130, 6267-71. [pdf]

17. Traaseth NJ, Verardi R, Veglia G (2008) Asymmetric methyl group labeling as a probe of membrane protein homo-oligomers by NMR spectroscopy. J Am Chem Soc 130, 2400-1. [pdf]

16. Masterson LR, Mascioni A, Traaseth NJ, Taylor SS, Veglia G (2008) Allosteric cooperativity in protein kinase A. Proc Natl Acad Sci 105, 506-11. [pdf]

15. Traaseth NJ, Ha KN, Verardi R, Shi L, Buffy JJ, Masterson LR, Veglia G (2008) Structural and dynamic basis of phospholamban and sarcolipin inhibition of Ca(2+)-ATPase. Biochemistry 47, 3-13. [pdf]

14. Ha KN, Traaseth NJ, Verardi R, Zamoon J, Cembran A, Karim CB, Thomas DD, Veglia G (2007) Controlling the inhibition of the sarcoplasmic Ca2+-ATPase by tuning phospholamban structural dynamics. J Biol Chem 282, 37205-14. [pdf]

13. Traaseth NJ, Verardi R, Torgersen KD, Karim CB, Thomas DD, Veglia G (2007) Spectroscopic validation of the pentameric structure of phospholamban. Proc Natl Acad Sci 104, 14676-81. [pdf]

12. Gor'kov PL, Chekmenev EY, Li C, Cotten M, Buffy JJ, Traaseth NJ, Veglia G, Brey WW (2007) Using low-E resonators to reduce RF heating in biological samples for static solid-state NMR up to 900 MHz. J Magn Reson 185, 77-93. [pdf]

11. Traaseth NJ, Buffy JJ, Zamoon J, Veglia G (2006) Structural dynamics and topology of phospholamban in oriented lipid bilayers using multidimensional solid-state NMR. Biochemistry 45, 13827-34. [pdf]

10. Buffy JJ, Traaseth NJ, Mascioni A, Gor'kov PL, Chekmenev EY, Brey WW, Veglia G (2006) Two-dimensional solid-state NMR reveals two topologies of sarcolipin in oriented lipid bilayers. Biochemistry 45, 10939-46 [pdf]

9. Traaseth NJ, Thomas DD, Veglia G (2006) Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2+)-ATPase complex. J Mol Biol 358, 1041-50. [pdf]

8. Buffy JJ, Buck-Koehntop BA, Porcelli F, Traaseth NJ, Thomas DD, Veglia G (2006) Defining the intramembrane binding mechanism of sarcolipin to calcium ATPase using solution NMR spectroscopy. J Mol Biol 358, 420-9. [pdf]

7. Metcalfe EE, Traaseth NJ, Veglia G (2006) Serine 16 Phosphorylation Induces an Order-to-Disorder Transition in Monomeric Phospholamban. Biochemistry 44, 4386-96. [pdf]

6. Haynes V, Elfering S, Traaseth N, Giulivi C (2004) Mitochondrial nitric-oxide synthase: enzyme expression, characterization, and regulation. J Bioenerg Biomembr 36, 341-6. [pdf]

5. Traaseth N, Elfering S, Solien J, Haynes V, Giulivi C (2004) Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle. Biochim Biophys Acta 1658, 64-71. [pdf]

4. Elfering SL, Haynes VL, Traaseth NJ, Ettl A, Giulivi C (2004) Aspects, mechanism, and biological relevance of mitochondrial protein nitration sustained by mitochondrial nitric oxide synthase. Am J Physiol Heart Circ Physiol 286, H22-9. [pdf]

3. Haynes V, Elfering SL, Squires RJ, Traaseth N, Solien J, Ettl A, Giulivi C (2003) Mitochondrial nitric-oxide synthase: role in pathophysiology. IUBMB Life 55, 599-603. [pdf]

2. Giulivi C, Traaseth NJ, Davies KJ (2003) Tyrosine oxidation products: analysis and biological relevance. Amino Acids 25, 227-32. [pdf]

1. Steffen M, Sarkela TM, Gybina AA, Steele TW, Traaseth NJ, Kuehl D, Giulivi C (2001) Metabolism of S-nitrosoglutathione in intact mitochondria. Biochem J 356, 395-402. [pdf]