Dental products manufacturer Heraeus Kulzer, Inc., has awarded NYUCD
a two-year, $120,000 grant to study the clinical performance and handling
characteristics of a new micro-hybrid composite resin claiming to
offer improved handling and fluorescence and an extensive range of
shades and opacities that can be closely matched to surrounding teeth
for both anterior and posterior restorations. Two one- bottle adhesives
that can be used interchangeably with the resin will also be evaluated.
The Bluestone Center for Clinical Research (BCCR) will be the site
for all research-related examinations and procedures.
investigators are Dr. Van P. Thompson, Professor and Chairman of
the Department of Biomaterials and Biomimetics and Acting Chairman
of the Department of Cariology and Operative Dentistry, and Dr.
Benjamin Godder, Clinical Associate Professor of Cariology and Operative
Dentistry. United States Public Health Service criteria are being
used to evaluate wear, marginal discoloration, and any post-operative
sensitivity of the Venus™ composite. This micro-hybrid composite
is available in 27 shades in three opacities, and is made from a
typical aromatic bifunctional methacrylate monomer (BIG-GMA) resin
combined with a unique filler that includes barium aluminum fluoride
glass and highly dispersed silicon dioxide. The two, 4-META-based
one-bottle adhesives to be evaluated are: Gluma® Comfort Bond, which
is used with a total etch bonding technique, and iBond™, a self-etching
70 subjects will be enrolled in order to study 120 restorations
on carious posterior teeth. Each tooth will be randomly assigned
to one or the other bonding agent. Most subjects are expected to
require at least two similar procedures, thus enabling a comparison
of Gluma Comfort Bond and iBond within the same individual. The
investigators plan to make the majority of the restorations on molars
to enable evaluation in a high-stress environment. Periodic independent
evaluation of the restorations will be conducted by calibrated teams
of faculty from the Department of Cariology and Operative Dentistry.