SIMONE DUARTE, DDS, MS, PhD
Assistant Professor of Basic Science and Craniofacial Biology
Focus is on the understanding and control of biofilms (aggregates of microorganisms in which cells adhere to each other or to a surface), using natural agents and other novel therapies that may be used for prevention and treatment of infectious diseases associated with biofilms, such as dental caries.
PROFESSIONAL BACKGROUND: .
Dr. Duarte’s laboratory studies the morphological and structural characterization of the biofilm matrix, using Environmental Scanning Electron Microscopy (ESEM) and Confocal Laser Scanning Microscopy (CLSM), quantifying the structural properties by analyzing the CLSM images using COMSTAT software. Rather than assessing their biological or biochemical influence, ESEM and CLSM offer direct insight into these agents’ influence on the biofilm matrix’s morphological and structural properties
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“Influence of Cranberry Proanthocyanidins on Formation of Biofilms by Streptococcus mutans on Saliva-Coated Apatitic Surface and Dental Caries Development in vivo.” Caries Research (2010).
“Structural and Molecular Basis of the Role of Starch and Sucrose in Streptococcus mutans Biofilm Development.” Applied and Environmental Microbiology (2009).
“Holographic Microrheology of Polysaccharides from Streptococcus mutans Biofilms.” Rheologica Acta (2009).