Under-40 award recognizes members’ significant contributions to urologic research.

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Xin Li, an assistant professor in the Department of Basic Science and Craniofacial Biology

Under-40 award recognizes members’ significant contributions to urologic research.

New York University College of Dentistry’s Xin Li, an assistant professor in the Department of Basic Science and Craniofacial Biology, has won the Society for Basic Urologic Research (SBUR) Young Investigator Award in recognition of her significant contributions to urologic research.

Selected from a pool of highly qualified candidates, the annual award recognizes significant contributions to urologic research from a SBUR member under the age of 40. The award will be presented at the Fall SBUR Annual Meeting being held in Ft. Lauderdale, FL, Nov 11-15

Dr. Li’s research focuses on causes and progression of prostate cancer and bone metastasis, observing metformin’s molecular mechanisms in mesenchymal and epithelial cells. Metformin is the first-line agent for type-2 diabetes which has been suggested to have anti-neoplasia efficacy and reducing fracture risks.

“We study metformin actions in altering gene expression and cell fate using type-2 diabetes and prostate cancer mouse models,” said Dr. Li. “Our recent study has revealed that metformin suppress c-MYC oncogene to inhibit prostate tumor growth in vitro and in vivo. We are funded by NCI to explore metformin application and mechanism as a novel chemopreventive agent against prostate cancer.”

Dr. Li and her team have also found that metformin can potentiate bone mesenchymal stromal cells and facilitate wound healing in bone. “We are aim to reveal further its functions in bone microenvironment during various conditions including: hyperglycemic, osteoporosis, fractures, and skeletal metastasis.

Dr. Li holds a secondary appointment in the Department of Urology at the NYU School of Medicine.

The Society for Basic Urologic Research (SBUR) is a society of scientists whose expertise includes the study of urologic cancers (prostate, bladder, kidney, testis, penis), the biology of prostate growth, kidney and bladder function, autoimmune urologic diseases, infectious diseases, neuro-urologic diseases, male reproductive biology, infertility and erectile dysfunction.

Members include molecular biologists, immunologists, epidemiologists, oncologists, biochemists and clinical urologic scientists. SBUR members serve on a wide variety of advisory panels, study sections, editorial boards and in the pharmaceutical industry. The SBUR organizes two annual meetings to share new findings at a multidisciplinary level, to promote interaction among members and other interested scientists and to highlight new areas of research and funding opportunities.

About New York University College of Dentistry Founded in 1865, New York University College of Dentistry (NYUCD) is the third oldest and the largest dental school in the US, educating more than 8 percent of all dentists. NYUCD has a significant global reach and provides a level of national and international diversity among its students that is unmatched by any other dental school.

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