New York University Skip to Content Skip to Search Skip to Navigation Skip to Sub Navigation

NIH Grant Awarded to the NYU College of Dentistry to Identify Bacteria Associated with Oral Cancer

November 8, 2010

The National Institute of Dental and Craniofacial Research, part of the NIH, has awarded a two-year, $245,000 grant to an New York University dental research team to identify bacteria in the oral cavity that may be associated with oral cancer. The team will collaborate with researchers at the NYU School of Medicine and the Memorial Sloan Kettering Cancer Center.

The principal investigator, Dr. Deepak Saxena, an Assistant Professor of Basic Science & Craniofacial Biology at the NYU College of Dentistry (NYUCD), said that the pilot study will compare the bacterial profiles of healthy, premalignant, and malignant oral tissue. Samples will be collected from 35 patients at NYUCD and the Memorial Sloan Kettering Cancer Center.

Dr. Saxena will use genetic sequencing to identify the bacteria present in each sample and to assess which of the bacteria spur an inflammatory process known to be associated with the development of oral cancer.

 “Our ultimate goal is to develop a risk assessment protocol for oral cancer based on the bacterial profile of premalignant lesions and malignant tumors,” said Dr. Saxena.

Plans call for a follow-up study involving a larger number of tissue samples.

Dr. Saxena’s co-investigators include Dr. Zoya Kurago, Assistant Professor of Oral and Maxillofacial Pathology, Radiology & Medicine; Dr. Yihong Li, Professor of Basic Science & Craniofacial Biology; Dr. Robert G. Norman, Research Associate Professor of Epidemiology & Health Promotion; and Dr. Peter Sacks, Professor of Basic Science & Craniofacial Biology, all of NYUCD. Additional co-investigators include Dr. Stuart M. Brown, Associate Professor of Cell Biology at the NYU School of Medicine, and Dr. Chery Estilo, Attending Dentist at the Memorial Sloan Kettering Cancer Institute Dental Service.

This Article is in the following Topics:
NYUToday-feature, Research News, College of Dentistry

Type: Article

Press Contact: Christopher James | (212) 998-6876

NIH Grant Awarded to the NYU College of Dentistry to Identify Bacteria Associated with Oral Cancer

Dr. Deepak Saxena


Search News



NYU In the News

Paying It Backward: NYU Alum Funds Scholarships

The Wall Street Journal profiled Trustee Evan Chesler on why he decided to chair the Momentum fund-raising campaign.

A Nobel Prize Party: Cheese, Bubbles, and a Boson

The New Yorker talked to Professor Kyle Cranmer and graduate student Sven Kreiss about NYU’s role in the discovery of the Higgs boson, which resulted in a Nobel prize for the scientists who predicted its existence.

The World as They Knew It

The New York Times reviewed the exhibit at the Institute for the Study of the Ancient World on how ancient Greeks and Romans mapped the known and unknown areas of their world.

Elite Institutions: Far More Diverse Than They Were 20 Years Ago

NYU made stronger gains over the last 20 years in increasing diversity than any other major research university, according to the Chronicle of Higher Education.

Program Seeks to Nurture ‘Data Science Culture’
at Universities

The New York Times reported on the multi-million collaboration among NYU and two other universities to harness the potential of Big Data, including an interview with Professor Yann LeCun, director of NYU’s Center for Data Science.

NYU Footer