New York University Skip to Content Skip to Search Skip to Navigation Skip to Sub Navigation

College of Dentistry and Polytechnic Institute Share Grant to Develop New Weapon Against Harmful Oral Bacteria

February 23, 2010


 

By Ami Finkelthal

Researchers from the College of Dentistry and the Polytechnic Institute of NYU have been awarded a one-year NYU-Polytechnic Institute Seed Grant for Collaborative Research to develop a new weapon against oral bacteria that cause dental caries and adhere to dental restorations, causing them to fail.


Co-principal investigators Dr. Simone Duarte, an Assistant Professor of Basic Science & Craniofacial Biology at the College of Dentistry, and Dr. Spencer Szu-pin Kuo, a Professor of Electrical & Computer Engineering at the Polytechnic Institute, are examining whether an air plasma torch can kill microorganisms that adhere to tooth surfaces and dental implants and veneers, penetrate inside root canal treatments, and attack other types of restorations.  Air plasma is a gaslike substance composed of oxygen, nitrogen, and electrons. The highly energized form of air plasma in the NYUCD-Polytechnic study contains free radicals, or reactive atoms and molecules, which can destroy microbes through chemical reactions. 


Dr. Kuo will build the torch and Dr. Duarte will assess whether the air plasma can prevent bacteria from attaching to tooth surfaces and restorative materials such as alumina, zirconia, and microwave- and light-cured resins.  Dr. Duarte and her co-investigator Dr. Deepak Saxena, an Assistant Professor of Basic Science & Craniofacial Biology at NYUCD, will also determine how much air plasma is needed to kill the microorganisms in vitro.


The NYUCD-Polytechnic investigators hypothesize that air plasma, which is used to kill bacteria deep inside burn wounds, could destroy microorganisms that cause dental caries and seep into root canal treatments and other dental restorations.  Implants and other prostheses could also be treated with air plasma to make their surfaces less susceptible to bacterial attachment.  If it proves effective, the torch would be tested in a subsequent clinical trial involving human subjects.

 

In addition to Dr. Saxena, Dr. Van Thompson, Professor and Chair of the NYUCD Department of Biomaterials & Biomimetics; Dr. Ramiro Murata, an Associate Research Scientist in Basic Science & Craniofacial Biology; and Mr. Cheng-Yen Chen, a PhD candidate in Electrical & Computer Engineering at the Polytechnic Institute, are co-investigators on the study.


Polytechnic University became affiliated with NYU in July 2007 and is now known as the Polytechnic Institute of NYU. Dr. Dianne Rekow, formerly Professor and Chair of NYUCD’s Department of Basic Science & Craniofacial Biology, and now Provost of the Polytechnic Institute of NYU, established the NYU-Polytechnic Institute Collaborative Research Grant Program to fund studies that can strengthen research at both institutions.



 

 

 

This Press Release is in the following Topics:
Research, Research News, College of Dentistry

Type: Press Release

Press Contact: Christopher James | (212) 998-6876

College of Dentistry and Polytechnic Institute Share Grant to Develop New Weapon Against Harmful Oral Bacteria

Search News



NYU In the News

CUSP Unveils its “Urban Observatory”

Crain’s New York Business profiled CUSP’s “Urban Observatory” that is continuously photographing lower Manhattan to gather scientific data.

Post-Sandy Upgrades at the Langone Medical Center

NY1 reported on the major post-Sandy upgrades and renovations made at the Medical Center to protect the hospital from future catastrophic storms.

Steinhardt Research Helps Solve Tough Speech Problems.

The Wall Street Journal reported on research at Steinhardt’s Department of Communicative Sciences and Disorders, including an interview with Assistant Professor Tara McAllister Byun, that uses ultrasound to help solve tough speech problems.

Times Column Lauds Professor Stevenson’s New Memoir

New York Times columnist Nicholas Kristof wrote a column about “Just Mercy,” a new memoir by Law Professor Bryan Stevenson, the founder of the Equal Justice Initiative, whom he noted has been called America’s Nelson Mandela.

Entrepreneurship Lab Opens at NYU

Crain’s New York Business covered the opening of the Mark and Debra Leslie Entrepreneurial eLab, which will be the headquarters for NYU’s Entrepreneurial Institute and all of the University’s programs aimed at promoting innovation and startups.

NYU Footer